Daniel Gusenleitner

Affiliations

Novartis Institutes for BioMedical Research, Cambridge, MA, USA.

Publications (10)

Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAF

The Lancet. Oncology

Avec: Reinhard Dummer , Jan C Brase , James Garrett , Catarina D Campbell , Eduard Gasal , Matthew Squires , Daniel Gusenleitner , Mario Santinami , Victoria Atkinson , Mario Mandalà , Vanna Chiarion-Sileni , Keith Flaherty , James Larkin , Caroline Robert , Richard Kefford , John M Kirkwood , Axel Hauschild , Dirk Schadendorf , Georgina V Long

Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i.

Nature medicine

Avec: Reinhard Dummer , Celeste Lebbé , Victoria Atkinson , Mario Mandalà , Paul D Nathan , Ana Arance , Erika Richtig , Naoya Yamazaki , Caroline Robert , Dirk Schadendorf , Hussein A Tawbi , Paolo A Ascierto , Antoni Ribas , Keith T Flaherty , Neha Pakhle , Catarina D Campbell , Daniel Gusenleitner , Aisha Masood , Jan C Brase , Eduard Gasal , Georgina V Long

Colocalization of cancer-associated biomarkers on single extracellular vesicles for early detection of cancer.

The Journal of molecular diagnostics : JMD

Avec: Daniel P Salem , Laura T Bortolin , Dan Gusenleitner , Jonian Grosha , Ibukunoluwapo O Zabroski , Kelly M Biette , Sanchari Banerjee , Christopher R Sedlak , Delaney M Byrne , Bilal F Hamzeh , MacKenzie S King , Lauren T Cuoco , Timothy Santos-Heiman , Gabrielle N Barcaskey , Katherine S Yang , Peter A Duff , Emily S Winn-Deen , Toumy Guettouche , Dawn R Mattoon , Eric K Huang , Randy W Schekman , Anthony D Couvillon , Joseph C Sedlak

A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies.

Oncoimmunology

Avec: Chia-Chi Lin , Elena Garralda , Patrick Schöffski , David S Hong , Lillian L Siu , Miguel Martin , Michela Maur , Rina Hui , Ross A Soo , Joanne Chiu , Tian Zhang , Brigette Ma , Chrisann Kyi , Daniel Sw Tan , Philippe A Cassier , John Sarantopoulos , Andrew Weickhardt , Richard D Carvajal , Jennifer Spratlin , Taito Esaki , Fréderic Rolland , Wallace Akerley , Barbara Deschler-Baier , Lawrence Rispoli , Tanay S Samant , Niladri Roy Chowdhury , Daniel Gusenleitner , Eunice L Kwak , Vasileios Askoxylakis , Filippo De Braud

Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma.

Nature cancer

Avec: Renáta Váraljai , Lisa Zimmer , Yahya Al-Matary , Paulien Kaptein , Lea J Albrecht , Batool Shannan , Jan C Brase , Daniel Gusenleitner , Teresa Amaral , Nina Wyss , Jochen Utikal , Lukas Flatz , Florian Rambow , Hans Christian Reinhardt , Jenny Dick , Daniel R Engel , Susanne Horn , Selma Ugurel , Wiebke Sondermann , Elisabeth Livingstone , Antje Sucker , Annette Paschen , Fang Zhao , Jan M Placke , Jasmin M Klose , Wolfgang P Fendler , Daniela S Thommen , Iris Helfrich , Dirk Schadendorf , Alexander Roesch

Improving specificity for ovarian cancer screening using a novel extracellular vesicle-based blood test - Performance in a training and verification cohort.

The Journal of molecular diagnostics : JMD

Avec: Emily S Winn-Deen , Laura T Bortolin , Daniel Gusenleitner , Kelly M Biette , Karen Copeland , Aleksandra Gentry-Maharaj , Sophia Apostolidou , Anthony D Couvillon , Daniel P Salem , Sanchari Banerjee , Jonian Grosha , Ibukunoluwapo O Zabroski , Christopher R Sedlak , Delaney M Byrne , Bilal F Hamzeh , MacKenzie S King , Lauren T Cuoco , Peter A Duff , Brendan J Manning , Troy B Hawkins , Dawn Mattoon , Toumy Guettouche , Steven J Skates , Amy Jamieson , Jessica N McAlpine , David Huntsman , Usha Menon

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma.

Blood

Avec: Gabriel K Griffin , Jason L Weirather , Margaretha G M Roemer , Mikel Lipschitz , Alyssa Kelley , Pei-Hsuan Chen , Daniel Gusenleitner , Erin Jeter , Christine Pak , Evisa Gjini , Bjoern Chapuy , Michael H Rosenthal , Jie Xu , Benjamin J Chen , Aliyah R Sohani , Scott B Lovitch , Jeremy S Abramson , Jeffrey J Ishizuka , Austin I Kim , Caron A Jacobson , Ann S LaCasce , Christopher D Fletcher , Donna Neuberg , Gordon J Freeman , F Stephen Hodi , Kyle Wright , Azra H Ligon , Eric D Jacobsen , Philippe Armand , Margaret A Shipp , Scott J Rodig

Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jan C Brase , Robert F H Walter , Alexander Savchenko , Daniel Gusenleitner , James Garrett , Tobias Schimming , Renata Varaljai , Deborah Castelletti , Ju Kim , Naveen Dakappagari , Ken Schultz , Caroline Robert , Georgina V Long , Paul D Nathan , Antoni Ribas , Keith T Flaherty , Boguslawa Karaszewska , Jacob Schachter , Antje Sucker , Kurt W Schmid , Lisa Zimmer , Elisabeth Livingstone , Eduard Gasal , Dirk Schadendorf , Alexander Roesch

Phase I/II study of the LAG-3 inhibitor ieramilimab (LAG525) ± anti-PD-1 spartalizumab (PDR001) in patients with advanced malignancies.

Journal for immunotherapy of cancer

Avec: Patrick Schöffski , Daniel S W Tan , Miguel Martín , María Ochoa-de-Olza , John Sarantopoulos , Richard D Carvajal , Chrisann Kyi , Taito Esaki , Amy Prawira , Wallace Akerley , Filippo De Braud , Rina Hui , Tian Zhang , Ross A Soo , Michela Maur , Andrew Weickhardt , Jürgen Krauss , Barbara Deschler-Baier , Allen Lau , Tanay S Samant , Tyler Longmire , Niladri Roy Chowdhury , Catherine A Sabatos-Peyton , Nidhi Patel , Radha Ramesh , Tiancen Hu , Ana Carion , Daniel Gusenleitner , Padmaja Yerramilli-Rao , Vasileios Askoxylakis , Eunice L Kwak , David S Hong

Spartalizumab or placebo in combination with dabrafenib and trametinib in patients with

Journal for immunotherapy of cancer

Avec: Hussein A Tawbi , Caroline Robert , Jan C Brase , Daniel Gusenleitner , Eduard Gasal , James Garrett , Alexander Savchenko , Güllü Görgün , Keith T Flaherty , Antoni Ribas , Reinhard Dummer , Dirk Schadendorf , Georgina V Long , Paul D Nathan , Paolo A Ascierto

Réseau de co-auteurs

Jan C Brase 5 collaborations

Dirk Schadendorf 5 collaborations

Eduard Gasal 4 collaborations

Caroline Robert 4 collaborations

Georgina V Long 4 collaborations

Reinhard Dummer 3 collaborations

James Garrett 3 collaborations

Paul D Nathan 3 collaborations

Antoni Ribas 3 collaborations

Keith T Flaherty 3 collaborations

Catarina D Campbell 2 collaborations

Victoria Atkinson 2 collaborations

Mario Mandalà 2 collaborations

Hussein A Tawbi 2 collaborations

Paolo A Ascierto 2 collaborations

Daniel P Salem 2 collaborations

Laura T Bortolin 2 collaborations

Jonian Grosha 2 collaborations

Ibukunoluwapo O Zabroski 2 collaborations

Kelly M Biette 2 collaborations

Sanchari Banerjee 2 collaborations

Christopher R Sedlak 2 collaborations

Delaney M Byrne 2 collaborations

Bilal F Hamzeh 2 collaborations

MacKenzie S King 2 collaborations

Lauren T Cuoco 2 collaborations

Peter A Duff 2 collaborations

Emily S Winn-Deen 2 collaborations

Toumy Guettouche 2 collaborations

Anthony D Couvillon 2 collaborations

Patrick Schöffski 2 collaborations

David S Hong 2 collaborations

Michela Maur 2 collaborations

Rina Hui 2 collaborations

Ross A Soo 2 collaborations

Tian Zhang 2 collaborations

Chrisann Kyi 2 collaborations

John Sarantopoulos 2 collaborations

Andrew Weickhardt 2 collaborations

Richard D Carvajal 2 collaborations

Taito Esaki 2 collaborations

Wallace Akerley 2 collaborations

Barbara Deschler-Baier 2 collaborations

Tanay S Samant 2 collaborations

Niladri Roy Chowdhury 2 collaborations

Eunice L Kwak 2 collaborations

Vasileios Askoxylakis 2 collaborations

Filippo De Braud 2 collaborations

Lisa Zimmer 2 collaborations

Elisabeth Livingstone 2 collaborations

Antje Sucker 2 collaborations

Alexander Roesch 2 collaborations

Alexander Savchenko 2 collaborations

Matthew Squires 1 collaboration

Mario Santinami 1 collaboration

Vanna Chiarion-Sileni 1 collaboration

Keith Flaherty 1 collaboration

James Larkin 1 collaboration

Richard Kefford 1 collaboration

John M Kirkwood 1 collaboration

Axel Hauschild 1 collaboration

Celeste Lebbé 1 collaboration

Ana Arance 1 collaboration

Erika Richtig 1 collaboration

Naoya Yamazaki 1 collaboration

Neha Pakhle 1 collaboration

Aisha Masood 1 collaboration

Dan Gusenleitner 1 collaboration

Timothy Santos-Heiman 1 collaboration

Gabrielle N Barcaskey 1 collaboration

Katherine S Yang 1 collaboration

Dawn R Mattoon 1 collaboration

Eric K Huang 1 collaboration

Randy W Schekman 1 collaboration

Joseph C Sedlak 1 collaboration

Chia-Chi Lin 1 collaboration

Elena Garralda 1 collaboration

Lillian L Siu 1 collaboration

Miguel Martin 1 collaboration

Joanne Chiu 1 collaboration

Brigette Ma 1 collaboration

Daniel Sw Tan 1 collaboration

Philippe A Cassier 1 collaboration

Jennifer Spratlin 1 collaboration

Fréderic Rolland 1 collaboration

Lawrence Rispoli 1 collaboration

Renáta Váraljai 1 collaboration

Yahya Al-Matary 1 collaboration

Paulien Kaptein 1 collaboration

Lea J Albrecht 1 collaboration

Batool Shannan 1 collaboration

Teresa Amaral 1 collaboration

Nina Wyss 1 collaboration

Jochen Utikal 1 collaboration

Lukas Flatz 1 collaboration

Florian Rambow 1 collaboration

Hans Christian Reinhardt 1 collaboration

Jenny Dick 1 collaboration

Daniel R Engel 1 collaboration

Susanne Horn 1 collaboration

Selma Ugurel 1 collaboration

Wiebke Sondermann 1 collaboration

Annette Paschen 1 collaboration

Fang Zhao 1 collaboration

Jan M Placke 1 collaboration

Jasmin M Klose 1 collaboration

Wolfgang P Fendler 1 collaboration

Daniela S Thommen 1 collaboration

Iris Helfrich 1 collaboration

Karen Copeland 1 collaboration

Aleksandra Gentry-Maharaj 1 collaboration

Sophia Apostolidou 1 collaboration

Brendan J Manning 1 collaboration

Troy B Hawkins 1 collaboration

Dawn Mattoon 1 collaboration

Steven J Skates 1 collaboration

Amy Jamieson 1 collaboration

Jessica N McAlpine 1 collaboration

David Huntsman 1 collaboration

Usha Menon 1 collaboration

Gabriel K Griffin 1 collaboration

Jason L Weirather 1 collaboration

Margaretha G M Roemer 1 collaboration

Mikel Lipschitz 1 collaboration

Alyssa Kelley 1 collaboration

Pei-Hsuan Chen 1 collaboration

Erin Jeter 1 collaboration

Christine Pak 1 collaboration

Evisa Gjini 1 collaboration

Bjoern Chapuy 1 collaboration

Michael H Rosenthal 1 collaboration

Jie Xu 1 collaboration

Benjamin J Chen 1 collaboration

Aliyah R Sohani 1 collaboration

Scott B Lovitch 1 collaboration

Jeremy S Abramson 1 collaboration

Jeffrey J Ishizuka 1 collaboration

Austin I Kim 1 collaboration

Caron A Jacobson 1 collaboration

Ann S LaCasce 1 collaboration

Christopher D Fletcher 1 collaboration

Donna Neuberg 1 collaboration

Gordon J Freeman 1 collaboration

F Stephen Hodi 1 collaboration

Kyle Wright 1 collaboration

Azra H Ligon 1 collaboration

Eric D Jacobsen 1 collaboration

Philippe Armand 1 collaboration

Margaret A Shipp 1 collaboration

Scott J Rodig 1 collaboration

Robert F H Walter 1 collaboration

Tobias Schimming 1 collaboration

Renata Varaljai 1 collaboration

Deborah Castelletti 1 collaboration

Ju Kim 1 collaboration

Naveen Dakappagari 1 collaboration

Ken Schultz 1 collaboration

Boguslawa Karaszewska 1 collaboration

Jacob Schachter 1 collaboration

Kurt W Schmid 1 collaboration

Daniel S W Tan 1 collaboration

Miguel Martín 1 collaboration

María Ochoa-de-Olza 1 collaboration

Amy Prawira 1 collaboration

Jürgen Krauss 1 collaboration

Allen Lau 1 collaboration

Tyler Longmire 1 collaboration

Catherine A Sabatos-Peyton 1 collaboration

Nidhi Patel 1 collaboration

Radha Ramesh 1 collaboration

Tiancen Hu 1 collaboration

Ana Carion 1 collaboration

Padmaja Yerramilli-Rao 1 collaboration

Güllü Görgün 1 collaboration